{"product_id":"ace-031","title":"ACE-031","description":"\u003cp\u003eACE-031 is a recombinant fusion protein that combines the extracellular ligand-binding domain of activin receptor type IIB (ActRIIB) with the Fc portion of human IgG1. This structurally defined soluble receptor construct is designed for experimental investigation of ligand-receptor interactions within the transforming growth factor-beta (TGF-β) superfamily. In biochemical and cellular research systems,\u003c\/p\u003e\n\u003cp\u003eACE-031 functions as a decoy receptor capable of binding select TGF-β family ligands, including myostatin (GDF-8) and activins. By binding these ligands, ACE-031 prevents their interaction with endogenous cell-surface receptors, facilitating studies of ligand binding affinity, downstream signaling modulation, and pathway inhibition under controlled conditions. The observed molecular responses depend on experimental design, ligand availability, and model system, and are used primarily to explore mechanisms of TGF-β signaling rather than to produce biological or physiological outcomes.\u003c\/p\u003e\n\u003ch3\u003eApplications in Research\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAs a molecular tool for studying myostatin and activin ligand binding\u003c\/li\u003e\n\u003cli\u003eInvestigation of TGF-β superfamily signaling regulation\u003c\/li\u003e\n\u003cli\u003eIn vitro studies examining receptor-ligand sequestration mechanisms\u003c\/li\u003e\n\u003cli\u003eUse as a reference construct in fusion protein and decoy receptor research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eForm: Lyophilised powder\u003c\/li\u003e\n\u003cli\u003ePurity: ≥99% verified by HPLC\u003c\/li\u003e\n\u003cli\u003eStorage: −20°C, protected from light and moisture\u003c\/li\u003e\n\u003cli\u003eAvailable size: 10mg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e⚠ \u003cstrong\u003eFor research purposes only.\u003c\/strong\u003e This product is not intended for human or veterinary use, consumption, or self-administration. Must be handled by qualified professionals in a suitable laboratory environment. Not evaluated by the MHRA or any regulatory authority for therapeutic use.\u003c\/p\u003e","brand":"CoreX Peptides","offers":[{"title":"Default Title","offer_id":58509441761605,"sku":"ACE-031","price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1075\/8950\/1253\/files\/ACE-031.jpg?v=1784031812","url":"https:\/\/www.corexpeptides.co.uk\/products\/ace-031","provider":"CoreX Peptides","version":"1.0","type":"link"}