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CoreX Peptides

IGF1-LR3

IGF1-LR3

Regular price £49.99 GBP
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IGF-LR3 (Insulin-like Growth Factor 1, Long Arg3) is a research-grade synthetic analogue of human IGF-1 modified with a 13-amino-acid N-terminal extension and an arginine substitution at position 3. These two modifications dramatically reduce affinity for IGF-binding proteins (IGFBPs), extending its functional half-life and increasing receptor availability in research settings. It is one of the most extensively studied IGF-1 analogues in cellular proliferation and anabolic signalling research.

Available in 1mg vials

RESEARCH APPLICATIONS INCLUDE:

  • Cellular proliferation and myoblast differentiation studies
  • IGF-1 receptor binding kinetics and downstream PI3K/Akt signalling
  • Glucose uptake and insulin sensitivity pathway research
  • Muscle protein synthesis and anti-catabolic mechanism investigation
  • Comparative research vs native IGF-1 and other growth factor analogues
  • mTOR pathway activation and cellular growth signalling studies

PRODUCT SPECIFICATIONS:

  • Form: Lyophilised powder
  • Purity: ≥99% 
  • Storage: −20°C, protected from light and moisture
  • Available strength: 1mg

For research purposes only. This product is not intended for human or veterinary use, consumption, or self-administration. Must be handled by qualified professionals in a suitable laboratory environment. Not evaluated by the MHRA or any regulatory authority for therapeutic use

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Frequently Asked Questions

What are the main benefits of using IGF1-LR3 in cellular proliferation research?
IGF1-LR3 enhances cellular proliferation and myoblast differentiation due to its extended half-life and increased receptor availability, making it ideal for growth factor research and cell growth studies.
How does IGF1-LR3's modification improve its performance in receptor binding studies?
The arginine substitution and N-terminal extension in IGF1-LR3 reduce its affinity for IGF-binding proteins, resulting in improved receptor binding kinetics and more accurate receptor binding studies.
What should I consider when storing IGF1-LR3 to maintain its stability?
Store IGF1-LR3 lyophilised powder at -20°C, protected from light and moisture to preserve its purity and activity for research applications. Proper storage ensures consistent experimental results.