CoreX Peptides
Kisspeptin-10
Kisspeptin-10
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Kisspeptin-10 is a synthetic decapeptide corresponding to the C-terminal region of the endogenous KiSS-1 gene product. It represents the minimal bioactive fragment commonly used in research settings to study kisspeptin-mediated signalling independent of longer precursor peptides.
In biochemical and cellular research systems, Kisspeptin-10 interacts with the KISS1 receptor (also known as GPR54), a G-protein-coupled receptor expressed in hypothalamic and peripheral tissues. Experimental studies investigate receptor binding, downstream signalling cascades, and neuroendocrine pathway activation under controlled conditions. Observed molecular responses are dependent on experimental design, concentration, and model system, and are used to examine receptor-mediated signalling rather than defined physiological or clinical outcomes.
Applications in Research
- As a molecular probe for studying KISS1 receptor binding and activation
- Investigation of hypothalamic–pituitary–gonadal (HPG) axis signalling pathways
- In vitro studies examining neuropeptide-mediated receptor signalling
- Use as a reference compound in neuroendocrine and reproductive signalling research
Product specifications:
- Form: Lyophilised powder
- Purity: ≥99%
- Storage: −20°C, protected from light and moisture
- Available strength: 10mg
⚠ For research purposes only. This product is not intended for human or veterinary use, consumption, or self-administration. Must be handled by qualified professionals in a suitable laboratory environment. Not evaluated by the MHRA or any regulatory authority for therapeutic use
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