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CoreX Peptides

Kisspeptin-10

Kisspeptin-10

Regular price £27.99 GBP
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10mg
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Kisspeptin-10 is a synthetic decapeptide corresponding to the C-terminal region of the endogenous KiSS-1 gene product. It represents the minimal bioactive fragment commonly used in research settings to study kisspeptin-mediated signalling independent of longer precursor peptides.

In biochemical and cellular research systems, Kisspeptin-10 interacts with the KISS1 receptor (also known as GPR54), a G-protein-coupled receptor expressed in hypothalamic and peripheral tissues. Experimental studies investigate receptor binding, downstream signalling cascades, and neuroendocrine pathway activation under controlled conditions. Observed molecular responses are dependent on experimental design, concentration, and model system, and are used to examine receptor-mediated signalling rather than defined physiological or clinical outcomes.

Applications in Research

  • As a molecular probe for studying KISS1 receptor binding and activation
  • Investigation of hypothalamic–pituitary–gonadal (HPG) axis signalling pathways
  • In vitro studies examining neuropeptide-mediated receptor signalling
  • Use as a reference compound in neuroendocrine and reproductive signalling research

Product specifications:

  • Form: Lyophilised powder
  • Purity: ≥99% 
  • Storage: −20°C, protected from light and moisture
  • Available strength: 10mg 

For research purposes only. This product is not intended for human or veterinary use, consumption, or self-administration. Must be handled by qualified professionals in a suitable laboratory environment. Not evaluated by the MHRA or any regulatory authority for therapeutic use

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Frequently Asked Questions

What is Kisspeptin-10 and how is it used in research?
Kisspeptin-10 is a synthetic decapeptide used as a molecular probe in research to study kisspeptin-mediated signaling, including receptor activation and downstream pathways, mainly focusing on hypothalamic and reproductive neuroendocrine functions.
How does Kisspeptin-10 interact with the GPR54 receptor to influence neuroendocrine pathways?
Kisspeptin-10 interacts with the GPR54 receptor, activating signaling cascades that regulate the hypothalamic-pituitary-gonadal axis and neuropeptide pathways involved in reproductive hormone regulation.
What are the storage and handling requirements for Kisspeptin-10 in laboratory settings?
Kisspeptin-10 should be stored as a lyophilised powder at -20°C, protected from light and moisture, and handled only by qualified professionals in suitable laboratory conditions to ensure stability and purity.