Sermorelin

Sermorelin (GRF 1-29) is a synthetic peptide analogue of the naturally occurring Growth Hormone-Releasing Hormone (GHRH). It corresponds to the amino-terminal segment (first 29 amino acids) of the endogenous 44-amino acid GHRH hormone. Preclinical research identifies Sermorelin as a potent growth hormone secretagogue that stimulates the pituitary gland to secrete Growth Hormone (GH) in a pulsatile manner, mimicking physiological rhythms. Unlike HGH administration which bypasses the feedback loop, Sermorelin is investigated for its ability to preserve the hypothalamic-pituitary-somatotropic axis.

Research applications include:

• • Investigation of GHRH receptor binding and signalling pathways
  • Study of hypothalamic–pituitary axis regulation
  • In vitro comparison of truncated versus full-length GHRH peptides
  • Use as a reference compound in neuroendocrine and peptide signalling research

Product specifications:

• Form: Lyophilised powder
• Purity: ≥99%
• Storage: –20°C, protected from light and moisture
• Available strength: 5mg

⚠️ For research purposes only. This product is not intended for human or veterinary use, consumption, or self-administration. Handling must be performed by qualified professionals within a suitable laboratory environment. It has not been evaluated by regulatory authorities such as the MHRA for therapeutic applications.