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CoreX Peptides

Sermorelin

Sermorelin

Regular price £24.99 GBP
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Sermorelin (GRF 1-29) is a synthetic peptide analogue of the naturally occurring Growth Hormone-Releasing Hormone (GHRH). It corresponds to the amino-terminal segment (first 29 amino acids) of the endogenous 44-amino acid GHRH hormone. Preclinical research identifies Sermorelin as a potent growth hormone secretagogue that stimulates the pituitary gland to secrete Growth Hormone (GH) in a pulsatile manner, mimicking physiological rhythms. Unlike HGH administration which bypasses the feedback loop, Sermorelin is investigated for its ability to preserve the hypothalamic-pituitary-somatotropic axis.

Research applications include:

  • • Investigation of GHRH receptor binding and signalling pathways
    • Study of hypothalamic–pituitary axis regulation
    • In vitro comparison of truncated versus full-length GHRH peptides
    • Use as a reference compound in neuroendocrine and peptide signalling research

Product specifications:

  • Form: Lyophilised powder
  • Purity: ≥99%
  • Storage: –20°C, protected from light and moisture
  • Available strength: 5mg

 

⚠️ For research purposes only. This product is not intended for human or veterinary use, consumption, or self-administration. Handling must be performed by qualified professionals within a suitable laboratory environment. It has not been evaluated by regulatory authorities such as the MHRA for therapeutic applications.

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Frequently Asked Questions

What are the main research applications for Ipamorelin?
Ipamorelin is used in research for studying selective ghrelin receptor agonism, pulsatile growth hormone secretion, body composition, bone density, and neuroendocrine signaling without affecting cortisol or prolactin levels. It is also suitable for comparing GH secretagogue activity with compounds like Tesamorelin.
How should Ipamorelin be stored to maintain its quality?
Ipamorelin should be stored at −20°C, protected from light and moisture, to preserve its purity and effectiveness for research purposes.
How does Ipamorelin differ from other growth hormone secretagogues?
Ipamorelin is distinguished by its high selectivity for the ghrelin receptor, which allows it to stimulate growth hormone release without elevating cortisol or prolactin, unlike broader-acting GHRPs.
What is Sermorelin and how does it work?
Sermorelin (GRF 1-29) is a synthetic peptide that mimics the activity of the natural Growth Hormone-Releasing Hormone (GHRH). It stimulates the pituitary gland to secrete growth hormone in a pulsatile manner, similar to natural physiological rhythms.
What are the primary research uses of Sermorelin?
Research applications of Sermorelin include studying GHRH receptor signaling pathways, hypothalamic-pituitary axis regulation, comparing truncated versus full-length GHRH peptides in vitro, and serving as a reference compound in neuroendocrine and peptide signaling research.
What are the storage instructions for Sermorelin research-grade powder?
Sermorelin should be stored at –20°C and kept protected from light and moisture to maintain its purity and effectiveness.
Is Sermorelin suitable for human use?
No, Sermorelin is intended solely for research purposes and is not suitable for human or veterinary use, consumption, or self-administration.
What is the significance of the research-grade status of this Sermorelin product?
The research-grade status indicates that this Sermorelin is intended for laboratory and scientific research only, ensuring high purity and quality for accurate and reliable research results.